Channel TP

MTA1 HD New Frequency 2021

MTA1 HD New Frequency 2021 2018

TP.11222 H 12000

Metastasis-associated protein MTA1 is a protein that in humans is encoded by the MTA1 gene. MTA1 is the founding member of the MTA family of genes.[5][6] MTA1 is primarily localized in the nucleus but also found to be distributed in the extra-nuclear compartments.[7][8] MTA1 is a component of several chromatin remodeling complexes including the nucleosome remodeling and deacetylation complex (NuRD).[9][10] MTA1 regulates gene expression by functioning as a coregulator to integrate DNA-interacting factors to gene activity.[11] MTA1 participates in physiological functions in the normal and cancer cells.[12][13] MTA1 is one of the most upregulated proteins in human cancer and associates with cancer progression, aggressive phenotypes, and poor prognosis of cancer patients.

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